Saks Fifth Avenue has plans to open a department store in Calgary, Alberta, in January 2018.
It will be the third Canadian store and the first in Western Canada.
The 115,000ft² two-level store will be located in the CF Chinook Centre, a property of Cadillac Fairview.
The department store will offer women's designerwear, menswear, footwear, beauty products, jewellery, and handbags.
In addition, it will have a full service Fifth Avenue Club with private suites and personal shopping consultants.
Saks Fifth Avenue president Marc Metrick said: "Following our incredibly successful entry into Canada earlier this year, we are excited to bring Saks Fifth Avenue to Western Canada in 2018.
"Our strategy is to opportunistically open new stores where we have the customer, the right location and are able to deliver a consistent Saks brand edit focused on modern fashion.
"Calgary, specifically the CF Chinook Centre, fits this criteria and is a logical next step in our Canadian expansion."
Cadillac Fairview president and chief executive officer John Sullivan said: "We are thrilled to once again partner with Saks Fifth Avenue to bring their iconic brand to a Cadillac Fairview shopping centre.
"The addition of Saks to our Western portfolio will further enhance the premium shopping experience Canadians have come to expect from us."
Saks opened its first department stores in Canada at Toronto's Eaton Centre and Sherway Gardens in February.